Description
TENLIEX-20 contains Teneligliptin I.P. 20 mg in tablet form. Teneligliptin belongs to the DPP-4 inhibitor class of oral antidiabetic medicines. It helps improve blood glucose control in adults with type 2 diabetes mellitus by enhancing the body’s incretin response when blood glucose levels are elevated.
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Therapeutic Segment
Anti-Diabetic Therapy | Type 2 Diabetes Management | DPP-4 Inhibitors | Oral Antidiabetic Medicines | Blood Glucose Control
Uses of TENLIEX-20
TENLIEX-20 may be prescribed as part of a treatment plan for:
- Type 2 diabetes mellitus
- Improving blood glucose control alongside appropriate diet and exercise
- Patients requiring oral DPP-4 inhibitor therapy
- Glycaemic management when treatment with Teneligliptin is considered appropriate
- Combination diabetes therapy when prescribed with other antidiabetic medicines
Teneligliptin is intended for the management of type 2 diabetes and should not be used as a substitute for insulin in type 1 diabetes or for the treatment of diabetic ketoacidosis.
Key Benefits of TENLIEX-20
- DPP-4 inhibitor: Provides targeted inhibition of the dipeptidyl peptidase-4 enzyme.
- Supports blood glucose control: Helps improve glycaemic management in adults with type 2 diabetes.
- Teneligliptin 20 mg: Provides the strength supplied in TENLIEX-20.
- Glucose-dependent action: Its incretin-related effects are linked to blood glucose levels.
- Oral tablet formulation: Convenient administration as part of an individualized diabetes-care plan.
- May be used in combination therapy: Can form part of a broader diabetes treatment regimen when prescribed.
How TENLIEX-20 Works
Teneligliptin is a DPP-4 inhibitor. DPP-4 normally breaks down incretin hormones such as GLP-1 and GIP.
By inhibiting DPP-4, Teneligliptin helps prolong incretin activity. Consequently, the pancreas can increase insulin release in response to elevated blood glucose, while glucagon secretion can decrease when glucose levels are high.
This glucose-dependent mechanism helps support blood glucose control in people with type 2 diabetes.
Common Side Effects of TENLIEX-20
Some people may experience side effects during treatment. Reported or possible effects can include:
- Nausea
- Abdominal discomfort
- Constipation or diarrhoea
- Headache
- Dizziness
- Reduced appetite
- Mild gastrointestinal discomfort
- Low blood sugar, particularly when Teneligliptin is used with other medicines that can cause hypoglycaemia
Side effects can vary depending on whether Teneligliptin is used alone or together with other antidiabetic medicines.
Important Safety Information
Use TENLIEX-20 only according to the advice of a qualified healthcare professional.
- Continue regular blood glucose monitoring as recommended by your diabetes-care team.
- Tell your doctor if you have kidney or liver disease before starting treatment.
- Liver dysfunction, including increases in liver enzymes, has been identified as an important adverse reaction requiring appropriate monitoring in regulatory safety information for Teneligliptin.
- Seek medical attention for persistent or severe abdominal pain, particularly if accompanied by vomiting, because pancreatitis has been reported with DPP-4 inhibitors.
- Monitor for symptoms of hypoglycaemia, especially if TENLIEX-20 is combined with insulin or a sulfonylurea.
- Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you use.
- Discuss pregnancy or breastfeeding with your healthcare professional before using Teneligliptin.
- Maintain the recommended diet, physical activity and blood glucose monitoring plan alongside treatment.
- Do not change the dose or stop treatment without medical advice.
- If you develop persistent cough, breathing difficulty or fever during treatment, seek medical attention. Regulatory safety information for Teneligliptin has identified interstitial pneumonia as a rare but clinically significant adverse reaction.
For additional regulatory information, refer to the PMDA Tenelia 20 mg/40 mg product information.
Dosage & Administration
Take TENLIEX-20 exactly as prescribed by your healthcare professional.
The 20 mg strength is an established Teneligliptin dose. Regulatory assessment identified 20 mg as the usual dose in the Japanese development programme, although the appropriate regimen for an individual patient depends on the approved product information, treatment response, kidney and liver status, and any other antidiabetic medicines being used.
Take the tablet according to the prescribed schedule. It may be taken with or without food unless the product-specific prescribing information states otherwise.
Do not increase the dose, stop treatment or take an additional tablet without medical advice.
If you miss a dose, follow the instructions provided by your healthcare professional rather than taking a double dose.
Storage
- Store in a cool, dry place.
- Protect the tablets from excessive heat and moisture.
- Keep the tablets in their original packaging until use.
- Keep out of the sight and reach of children.
- Do not use after the expiry date printed on the pack.
