Description
MEXANIM-P contains Nimesulide 100 mg and Paracetamol 325 mg, a combination used for the short-term management of pain, inflammation and fever when prescribed by a healthcare professional. Nimesulide belongs to the non-steroidal anti-inflammatory drug (NSAID) group, while Paracetamol provides analgesic and antipyretic action. Because nimesulide carries important liver-safety precautions, treatment should follow the prescribed dose and duration.
For related tablet formulations and therapeutic segments, Medhexa Pharma Tablets can be referred to for additional product information.
Therapeutic Segment
Pain Management | Analgesics | Anti-inflammatory | Antipyretics
Uses of MEXANIM-P
MEXANIM-P may be prescribed for short-term symptomatic relief of:
- Acute pain
- Pain associated with inflammation
- Fever accompanied by body aches
- Musculoskeletal pain
- Certain painful inflammatory conditions
- Other acute painful conditions when considered appropriate by a healthcare professional
Nimesulide helps reduce pain and inflammation, while Paracetamol contributes to pain relief and fever reduction. Therefore, the combination can provide complementary symptomatic relief when both effects are required.
Key Benefits of Nimesulide and Paracetamol
- Contains Nimesulide 100 mg
- Contains Paracetamol 325 mg
- Combines anti-inflammatory and analgesic activity
- Helps manage acute pain and inflammatory symptoms
- Paracetamol also helps reduce fever
- Available in convenient tablet form
- Supplied in 10 × 10 BLISTER packaging
How MEXANIM-P Works
Nimesulide is an NSAID that reduces the production of prostaglandins involved in pain and inflammation. As a result, it helps reduce inflammatory discomfort and pain.
Paracetamol works mainly through central pain-relieving and fever-reducing mechanisms. Therefore, it complements the analgesic effect of nimesulide and can help lower fever.
Common Side Effects of Nimesulide and Paracetamol
Some people may experience:
- Nausea
- Indigestion
- Stomach discomfort
- Diarrhea
- Vomiting
- Headache
- Dizziness
- Skin rash
However, side effects vary between individuals. Nimesulide can cause gastrointestinal effects and, importantly, has a recognized risk of liver injury. Paracetamol can also cause serious liver damage when taken in excessive amounts.
Important Safety Information
Use MEXANIM-P only as directed by a doctor or pharmacist.
In particular, do not use nimesulide for longer than recommended. Indian regulatory guidance states that nimesulide use should ordinarily be restricted to 10 days, while European regulatory authorities have also emphasized second-line use, the lowest effective dose and the shortest possible duration because of liver-safety concerns.
MEXANIM-P should not be used in children below 12 years of age.
Tell your healthcare professional if you have liver disease, kidney problems, stomach ulcers, gastrointestinal bleeding, asthma triggered by NSAIDs, or a previous allergic reaction to painkillers. Nimesulide product information also lists hepatic and renal impairment among important contraindications.
Also, avoid taking additional medicines containing Paracetamol unless your doctor or pharmacist confirms that they are appropriate. Taking too much Paracetamol can cause serious liver damage.
Avoid combining MEXANIM-P with other NSAIDs unless specifically advised. Also inform your doctor about anticoagulants, corticosteroids and other regular medicines because they may increase the risk of adverse effects.
Stop the medicine and seek medical attention if you develop symptoms that may indicate liver injury, such as unusual tiredness, loss of appetite, persistent nausea, abdominal discomfort, dark urine or yellowing of the skin or eyes. Seek urgent care for severe allergic reactions, gastrointestinal bleeding or other serious symptoms.
For additional regulatory information regarding nimesulide safety, refer to the European Medicines Agency information on nimesulide.
Dosage & Administration
The appropriate dose and treatment duration depend on the patient’s condition, age, medical history and other medicines being taken. Therefore, take MEXANIM-P only in the dose prescribed by your healthcare professional.
Nimesulide product information commonly specifies 100 mg twice daily for adults, but treatment should remain short-term and follow the applicable product information and medical advice. Do not extend treatment or increase the dose on your own.
Take the tablet with water. Nimesulide is generally recommended with food.
Because MEXANIM-P also contains Paracetamol, check other medicines carefully to avoid taking additional Paracetamol-containing products. If you miss a dose, follow your healthcare professional’s instructions and do not take a double dose.
Storage
- Store MEXANIM-P in a cool and dry place.
- Protect the tablets from excessive heat and moisture.
- Keep the tablets in their original packaging until use.
- Keep out of reach of children.
- Follow the storage instructions printed on the product packaging.
