Description
TELHEX M 50 contains Telmisartan I.P. 40 mg and Metoprolol Succinate I.P. 50 mg XL in tablet form. This combination brings together an angiotensin II receptor blocker (ARB) and a beta-blocker to support blood pressure and cardiovascular management when combination therapy is prescribed. Telmisartan helps relax blood vessels by blocking the action of angiotensin II, while Metoprolol reduces the effects of adrenaline on the heart, helping slow the heart rate and reduce the workload on the heart.
For related cardiovascular and antihypertensive formulations, explore the Medhexa Pharma product range for pharmaceutical products and business enquiries.
Therapeutic Segment
Cardiovascular Care | Antihypertensive Therapy | ARBs | Beta-Blockers | Blood Pressure Management
Uses of TELHEX M 50
TELHEX M 50 may be prescribed as part of a treatment plan for:
- High blood pressure (hypertension)
- Patients requiring combination antihypertensive therapy
- Blood pressure control when treatment with a single medicine does not provide adequate control
- Selected cardiovascular conditions where an ARB and beta-blocker are considered appropriate
- Long-term cardiovascular management under medical supervision
Metoprolol Succinate extended-release tablets are also used for conditions such as angina and certain types of heart failure; however, the appropriate use of this combination depends on the patient’s diagnosis and the prescribing clinician’s assessment.
Key Benefits of TELHEX M 50
- Dual-action formulation: Combines an ARB with a beta-blocker.
- Telmisartan 40 mg: Helps block angiotensin II and promote blood-vessel relaxation.
- Metoprolol Succinate 50 mg XL: Helps reduce heart rate and cardiac workload through beta-adrenergic blockade.
- Blood pressure support: Provides complementary mechanisms for hypertension management.
- Extended-release formulation: Metoprolol Succinate XL is formulated for extended release and is generally administered once daily according to prescribing information.
- Combination convenience: Provides two cardiovascular medicines in one tablet when combination treatment is appropriate.
How TELHEX M 50 Works
Telmisartan belongs to the angiotensin II receptor blocker (ARB) class. It blocks the AT1 receptor, preventing angiotensin II from producing its usual vasoconstricting effects. This allows blood vessels to remain more relaxed and helps lower blood pressure.
Metoprolol Succinate is a beta-adrenergic blocker. It reduces the effects of sympathetic stimulation on the heart, which can slow the heart rate and reduce cardiac workload. These effects contribute to blood-pressure control and may also help reduce cardiac oxygen demand.
Therefore, TELHEX M 50 combines two different cardiovascular mechanisms to support blood pressure and heart-rate management when clinically appropriate.
Common Side Effects of TELHEX M 50
Some people may experience side effects while taking Telmisartan and Metoprolol. Possible effects include:
- Dizziness
- Headache
- Tiredness or weakness
- Slow heart rate
- Low blood pressure
- Nausea
- Diarrhoea
- Cold hands or feet
- Reduced exercise tolerance
- Sleep disturbances
Metoprolol commonly causes tiredness, dizziness and weakness, while beta-blockers may also cause cold hands and feet.
Important Safety Information
Use TELHEX M 50 only according to the advice of a qualified healthcare professional.
- Monitor blood pressure and heart rate regularly as advised.
- Telmisartan can cause low blood pressure, particularly in patients who are dehydrated or have reduced circulating blood volume.
- Telmisartan may affect kidney function and potassium levels, particularly in patients with kidney disease, heart failure or those taking medicines that increase potassium.
- Tell your doctor if you have kidney disease, liver disease, heart failure, low blood pressure or electrolyte abnormalities.
- Avoid potassium supplements or potassium-containing salt substitutes unless specifically recommended by your healthcare professional.
- Combining an ARB with another medicine that blocks the renin-angiotensin system requires careful medical consideration because of potential kidney and potassium-related risks.
- Telmisartan should not be used during pregnancy. If pregnancy occurs, contact your healthcare professional promptly because medicines acting on the renin-angiotensin system can cause fetal harm.
- Metoprolol can cause slow heart rate and low blood pressure. Tell your doctor if you have bradycardia, heart-conduction problems or certain heart conditions.
- Metoprolol should not be stopped suddenly without medical advice because abrupt withdrawal can worsen some cardiovascular conditions.
- Beta-blockers can sometimes mask warning symptoms of low blood sugar, particularly in patients with diabetes.
- Tell your healthcare professional if you have asthma or other breathing problems because beta-blockers require appropriate clinical consideration.
- Inform your doctor before surgery or general anaesthesia because Metoprolol can affect heart rate and blood pressure.
- Avoid driving or operating machinery if the medicine causes dizziness or unusual tiredness.
- Tell your healthcare professional about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you use.
For additional information about Metoprolol, refer to the NHS guidance on Metoprolol.
Dosage & Administration
Take TELHEX M 50 exactly as prescribed by your healthcare professional.
Metoprolol Succinate extended-release tablets are generally administered once daily, with dosage adjusted according to the patient’s response and tolerability. Telmisartan dosing also requires individual consideration. Therefore, the exact regimen for TELHEX M 50 should follow the approved product information and the prescription provided by the healthcare professional.
The XL tablet should be taken as directed and should not be crushed or altered in a way that affects its extended-release characteristics.
Take the medicine at approximately the same time each day unless your healthcare professional provides different instructions.
Do not change the dose, stop treatment or take additional tablets without medical advice.
If you miss a dose, follow the instructions provided by your healthcare professional. Do not take a double dose to make up for a missed tablet.
Storage
- Store in a cool, dry place.
- Protect the tablets from excessive heat and moisture.
- Keep the tablets in their original packaging until use.
- Keep out of the sight and reach of children.
- Do not use after the expiry date printed on the pack.
