TELHEX-H

Description

TELHEX-H contains Telmisartan I.P. 40 mg and Hydrochlorothiazide I.P. 12.5 mg in tablet form. This combination brings together an angiotensin II receptor blocker (ARB) and a thiazide diuretic for blood pressure management. Telmisartan helps block the action of angiotensin II and promotes blood-vessel relaxation, while Hydrochlorothiazide increases the excretion of sodium and water through the kidneys. Together, they provide complementary antihypertensive effects when combination therapy is appropriate.

For related cardiovascular and hypertension formulations, explore the Medhexa Pharma product range for pharmaceutical products and business enquiries.

Therapeutic Segment

Cardiovascular Care | Antihypertensive Therapy | Blood Pressure Management | ARBs | Diuretics

Uses of TELHEX-H

TELHEX-H may be prescribed as part of a treatment plan for:

• High blood pressure (hypertension)
• Patients requiring combination antihypertensive therapy
• Blood pressure that remains inadequately controlled with appropriate single-agent treatment
• Patients who require additional blood-pressure reduction after treatment with an ARB or another antihypertensive medicine
• Long-term blood pressure management when the combination is clinically appropriate

Controlling high blood pressure can help reduce the risk of cardiovascular complications such as stroke and heart attack. The exact treatment plan depends on the patient’s blood pressure, medical history, response to therapy and other cardiovascular risk factors.

Key Benefits of TELHEX-H

• Dual-action antihypertensive therapy: Combines Telmisartan and Hydrochlorothiazide through complementary mechanisms.
• Telmisartan 40 mg: Blocks angiotensin II at AT1 receptors and helps reduce blood-vessel constriction.
• Hydrochlorothiazide 12.5 mg: Promotes sodium and water excretion, supporting blood-pressure reduction.
• Combination convenience: Provides two antihypertensive agents in one tablet.
• Supports ongoing blood pressure management: May be used when combination treatment is considered appropriate.
• Convenient oral formulation: Supplied as an easy-to-administer tablet.

How TELHEX-H Works

Telmisartan is an angiotensin II receptor blocker (ARB). It selectively blocks the action of angiotensin II at the AT1 receptor. This reduces angiotensin II-mediated vasoconstriction and lowers the activity of mechanisms that can increase blood pressure. As a result, blood vessels relax and blood pressure decreases.

Hydrochlorothiazide is a thiazide diuretic. It increases the renal excretion of sodium and water, which reduces fluid volume and contributes to lower blood pressure.

The two ingredients therefore work through complementary pathways to support blood pressure control.

Common Side Effects of TELHEX-H

Some people may experience side effects during treatment. Possible effects include:

• Dizziness
• Headache
• Fatigue
• Nausea
• Stomach discomfort
• Diarrhoea
• Increased urination
• Low blood pressure
• Changes in blood electrolyte levels

Hydrochlorothiazide can affect sodium and potassium levels, while Telmisartan can also affect potassium levels and kidney function. Healthcare professionals may monitor blood pressure, kidney function and electrolytes when clinically appropriate.

Important Safety Information

Use TELHEX-H only according to the advice of a qualified healthcare professional.

Blood Pressure and Dehydration

TELHEX-H can lower blood pressure and may cause dizziness, especially when treatment begins or when the body has lost fluids.

Tell your doctor if you experience significant vomiting, diarrhoea, excessive sweating or other conditions that may cause dehydration.

Kidney Function and Electrolytes

Telmisartan and Hydrochlorothiazide can affect kidney function and electrolyte levels. Your healthcare professional may monitor kidney function, potassium, sodium and other laboratory values when appropriate.

Tell your doctor if you have kidney disease, electrolyte abnormalities or a history of significant dehydration.

Potassium Precautions

Telmisartan may increase potassium levels, whereas Hydrochlorothiazide may reduce potassium levels. The overall effect varies between individuals.

Do not use potassium supplements or potassium-containing salt substitutes unless your healthcare professional recommends them.

Liver-Related Precautions

Tell your doctor if you have liver disease or biliary obstruction. Telmisartan/Hydrochlorothiazide combination therapy requires appropriate medical supervision in patients with hepatic impairment. Severe hepatic impairment requires particular caution and may affect whether this combination is suitable.

Important Medicine Interactions

Tell your healthcare professional about all prescription medicines, over-the-counter medicines, vitamins and supplements you take.

Potential interactions include:

• Other antihypertensive medicines
• Potassium supplements
• Potassium-containing salt substitutes
• Potassium-sparing diuretics
• Lithium
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Medicines that affect kidney function or electrolyte balance

Your healthcare professional can determine whether treatment adjustments or additional monitoring are necessary.

Pregnancy

Telmisartan should not be used during pregnancy. Medicines that act directly on the renin-angiotensin system can cause fetal harm. Tell your healthcare professional if you are pregnant, planning pregnancy or become pregnant during treatment.

Dosage & Administration

Take TELHEX-H exactly as prescribed by your healthcare professional.

The appropriate dose depends on the patient’s blood pressure, previous antihypertensive treatment, kidney and liver function, response to therapy and other medicines.

The Telmisartan 40 mg/Hydrochlorothiazide 12.5 mg strength is an established combination and is generally administered once daily. However, the exact regimen should follow the prescription and approved product information applicable to the patient. (dailymed.nlm.nih.gov)

Take the tablet with water and follow the dosing schedule provided by your healthcare professional.

Do not change the dose or stop treatment without medical advice. If you miss a dose, follow your healthcare professional’s instructions rather than taking an extra tablet.

Storage

• Store TELHEX-H in a cool, dry place.
• Protect the tablets from excessive heat and moisture.
• Keep the tablets in their original ALU-ALU packaging until use.
• Protect from direct sunlight and excessive moisture.
• Keep the tablets in the blister until immediately before administration.
• Keep out of the sight and reach of children.
• Do not use the product after the expiry date printed on the pack.