Description
MEXAXON-S 375 contains Ceftriaxone 250 mg & Sulbactam 125 mg Injection in a 1 VIAL × 10 ML pack. Ceftriaxone is a cephalosporin antibiotic that acts against susceptible bacteria, while Sulbactam helps inhibit certain beta-lactamase enzymes.
This combination may be prescribed for selected bacterial infections and other clinical situations when appropriate. You can also explore the MedHexa Pharma Products range for other pharmaceutical formulations.
Therapeutic Segment
Antibiotic | Anti-Infective | Cephalosporin | Injectable Antibiotic
Uses of MEXAXON-S 375
MEXAXON-S 375 may be prescribed for selected bacterial infections caused by susceptible organisms.
Depending on the clinical condition, Ceftriaxone-based treatment may be used for:
- Meningitis caused by susceptible bacteria
- Gonorrhea
- Septicemia and serious bloodstream infections
- Selected bacterial infections requiring injectable antibiotic treatment
- Surgical prophylaxis when specifically prescribed by a healthcare professional
However, the exact indication depends on the diagnosis, causative organism and clinical condition. Therefore, this injection should be administered only under appropriate medical supervision.
Key Benefits of MEXAXON-S 375
MEXAXON-S 375 combines Ceftriaxone with Sulbactam to provide antibacterial activity against susceptible organisms.
- Contains Ceftriaxone 250 mg
- Contains Sulbactam 125 mg
- Provides antibacterial activity against susceptible bacteria
- May be used in selected serious bacterial infections
- May be prescribed for meningitis caused by susceptible organisms
- May be used for gonorrhea when clinically appropriate
- Sulbactam helps inhibit certain beta-lactamase enzymes
- Injectable formulation for professional medical use
Furthermore, Sulbactam may help protect the activity of Ceftriaxone against certain beta-lactamase-producing bacteria. As a result, the combination can provide useful antibacterial coverage when the causative organisms are susceptible.
How the Combination Works
Ceftriaxone belongs to the third-generation cephalosporin group of antibiotics. It interferes with bacterial cell-wall synthesis, which can stop susceptible bacteria from growing and surviving.
Sulbactam acts as a beta-lactamase inhibitor. Some bacteria produce beta-lactamase enzymes that can break down certain beta-lactam antibiotics. Sulbactam inhibits some of these enzymes and may therefore help maintain the antibacterial activity of Ceftriaxone.
Together, the ingredients provide antibacterial activity against selected susceptible organisms.
MEXAXON-S 375 Side Effects
Like other injectable antibiotics, this medicine may cause side effects in some patients.
Possible side effects include:
- Pain or discomfort at the injection site
- Diarrhea
- Nausea
- Vomiting
- Abdominal discomfort
- Headache
- Skin rash
- Changes in liver enzyme levels
Most patients tolerate Ceftriaxone-based treatment well. However, serious allergic reactions can occur rarely.
Seek immediate medical attention if you experience difficulty breathing, swelling of the face or throat, severe skin reactions or severe and persistent diarrhea.
MEXAXON-S 375 Safety Information
MEXAXON-S 375 should be administered only by a qualified healthcare professional.
Before treatment, inform your doctor if you:
- Have an allergy to Ceftriaxone, Sulbactam, cephalosporins, penicillins or other beta-lactam antibiotics
- Have kidney or liver problems
- Have a history of gastrointestinal disease, particularly colitis
- Have previously experienced a serious reaction to antibiotics
- Are pregnant or breastfeeding
- Take prescription or over-the-counter medicines
In addition, tell your healthcare professional about all medicines and supplements you currently use.
Antibiotics do not treat viral infections such as the common cold or flu. Therefore, use this medicine only when a healthcare professional determines that antibiotic treatment is appropriate.
Do not stop an antibiotic course early unless your healthcare professional advises you to do so.
For additional information about Ceftriaxone, refer to DailyMed Ceftriaxone Drug Information.
Dosage and Administration
MEXAXON-S 375 should be administered according to the prescription and instructions of a qualified healthcare professional.
- The injection should be prepared and administered by trained medical personnel.
- The route of administration should follow the approved product instructions.
- The dose depends on the type and severity of infection, age, body weight and clinical condition.
- Do not self-administer the injection.
- Do not change the prescribed dose or treatment duration without medical advice.
- Complete the prescribed treatment unless your healthcare professional advises otherwise.
For surgical prophylaxis, the timing and dose should follow the healthcare professional’s specific instructions.
Ceftriaxone 250 mg & Sulbactam 125 mg Injection Information
MEXAXON-S 375 combines Ceftriaxone 250 mg and Sulbactam 125 mg in injectable form.
Ceftriaxone interferes with bacterial cell-wall formation, while Sulbactam inhibits certain beta-lactamase enzymes. Therefore, the combination may help manage selected bacterial infections caused by susceptible organisms.
Because antibiotic selection depends on the infection and bacterial susceptibility, a healthcare professional should determine whether this combination is appropriate.
Storage
- Store MEXAXON-S 375 according to the conditions stated on the product label.
- Keep the vial in its original packaging until use.
- Protect from excessive heat and moisture.
- Keep away from direct sunlight.
- Keep out of reach of children.
- Do not use the product after the expiry date.
- Follow the specific storage instructions provided with the product.
