Description
MEXAPAN-40 Injection contains Pantoprazole Sodium I.P. equivalent to Pantoprazole 40 mg in a lyophilized powder formulation. Pantoprazole belongs to the proton pump inhibitor (PPI) class and reduces gastric acid production. Doctors may choose intravenous pantoprazole when a patient requires acid suppression and cannot take oral therapy.
MEXAPAN-40 Injection provides Pantoprazole 40 mg for IV use only and requires administration by a qualified healthcare professional. The supplied pack also includes a 10 mL ampoule of Sodium Chloride Injection 0.9% w/v for reconstitution.
For related pharmaceutical formulations and therapeutic segments, explore the Medhexa Pharma product range.
Therapeutic Segment
Gastrointestinal Care | Proton Pump Inhibitors | Acid-Related Disorders
Uses of MEXAPAN-40 Injection
MEXAPAN-40 Injection may help manage acid-related gastrointestinal conditions when a physician considers intravenous pantoprazole appropriate.
The product information supplied with the pack lists these clinical areas:
- NSAID-induced gastritis
- Non-ulcer dyspepsia
- Functional dyspepsia
- Erosive esophagitis
In addition, healthcare professionals may use intravenous pantoprazole for selected patients with gastroesophageal reflux disease and erosive esophagitis when oral treatment does not provide a suitable option.
Therefore, the physician should determine the appropriate indication, treatment duration and administration schedule according to the patient’s condition.
Key Benefits of MEXAPAN-40 Injection
- Provides Pantoprazole 40 mg equivalent as Pantoprazole Sodium I.P.
- Reduces gastric acid secretion through proton pump inhibition.
- Provides an intravenous option when oral acid-suppression therapy cannot be used.
- Comes as a lyophilized powder for injection that requires reconstitution before administration.
- Supports acid-suppression therapy in selected gastrointestinal conditions.
- Comes in a convenient single-vial presentation for professional use.
How MEXAPAN-40 Injection Works
Pantoprazole works by targeting the acid-producing cells in the stomach.
First, pantoprazole reaches the gastric parietal cells. It then inhibits the H+/K+-ATPase proton pump, which controls the final stage of gastric acid secretion. As a result, the stomach produces less acid.
Consequently, reduced acid exposure can help control acid-related symptoms and support healing in conditions where excessive gastric acid contributes to the problem.
Moreover, intravenous administration allows pantoprazole to enter systemic circulation without relying on absorption through the gastrointestinal tract. This makes the injectable form useful in selected clinical situations where oral administration presents a problem.
Common Side Effects of MEXAPAN-40 Injection
Some patients may experience mild or temporary side effects, including:
- Headache
- Diarrhea
- Nausea
- Abdominal discomfort
- Vomiting
- Dizziness
- Injection-site or administration-related reactions
However, serious reactions can occur in rare cases. These may include severe allergic reactions, kidney inflammation and severe diarrhea associated with Clostridioides difficile.
Therefore, patients should seek immediate medical attention if they develop breathing difficulty, facial or throat swelling, severe skin reactions, persistent severe diarrhea or other serious symptoms.
Important Safety Information
Prescription medicine: MEXAPAN-40 Injection carries a Schedule H prescription-drug warning. A registered medical practitioner must prescribe this medicine, and retail sale requires a valid prescription.
IV use only: A qualified healthcare professional must administer MEXAPAN-40 Injection through the intravenous route.
Allergy: Patients with known hypersensitivity to pantoprazole, substituted benzimidazoles or any component of the formulation should not receive this medicine.
Kidney safety: Pantoprazole and other proton pump inhibitors can cause acute tubulointerstitial nephritis in some patients. Therefore, unexplained changes in kidney function require prompt medical evaluation.
Long-term treatment: Prolonged PPI therapy can affect vitamin B12 and magnesium levels and may increase fracture risk in certain patients. Consequently, physicians should review the need for long-term treatment regularly.
Drug interactions: Pantoprazole can interact with certain medicines. Patients should tell their doctor about all prescription medicines, over-the-counter products and supplements they currently use.
Pregnancy and breastfeeding: Patients who are pregnant, planning pregnancy or breastfeeding should consult their healthcare professional before receiving pantoprazole.
For detailed prescribing and safety information, refer to the official DailyMed Pantoprazole Sodium Injection information.
Dosage & Administration
Dosage:
As directed by the Physician.
The treating physician should determine the appropriate dose and treatment duration according to the patient’s condition. A qualified healthcare professional should administer MEXAPAN-40 Injection intravenously.
Direction for use as stated on the supplied product information:
- First, reconstitute the vial with the 10 mL ampoule of Sodium Chloride Injection 0.9% w/v supplied in the pack.
- Prick the Sodium Chloride ampoule for injection only once.
- Discard the Sodium Chloride ampoule after use.
- Next, inspect the reconstituted solution before administration.
- If you see any particle in the vial after dissolving the contents, do not use the product and return it for replacement.
- Use the reconstituted solution immediately and do not store it, as directed on the product pack.
- Administer the prepared solution through the intravenous route only.
Storage
Store MEXAPAN-40 Injection:
- Protect the product from light and moisture.
- Keep the product at a temperature not exceeding 30°C.
- Keep the vial in its original packaging until use.
- Keep the medicine out of reach of children.
After reconstitution, use the solution immediately and do not store it, according to the product instructions.
Furthermore, do not use the product if the vial appears damaged, the reconstituted solution contains visible particles, or the product has passed its expiry date.
