Description
MEXACOF-DX is a combination cough and cold formulation containing Dextromethorphan Hydrobromide I.P. 10 mg, Chlorpheniramine Maleate I.P. 2 mg and Phenylephrine HCl I.P. 5 mg. The combination provides cough-suppressant, antihistamine and nasal-decongestant activity for symptomatic relief of cough and associated cold or allergy symptoms.
MEXACOF-DX is supplied as an oral liquid formulation in a 60 ML pack with carton.
For related formulations and therapeutic segments, explore the Medhexa Pharma Products range for additional respiratory and pharmaceutical formulations.
Therapeutic Segment
Respiratory Care | Cough & Cold | Antitussive | Antihistamine | Nasal Decongestant | Oral Liquid
Uses of MEXACOF-DX
MEXACOF-DX may provide temporary symptomatic relief of cough and associated upper-respiratory symptoms.
It may be used for:
- Cough associated with minor throat or bronchial irritation
- Runny nose
- Sneezing
- Nasal congestion
- Itching of the nose or throat associated with cold or allergy symptoms
- Watery or itchy eyes associated with allergic symptoms
The individual ingredients have complementary actions: dextromethorphan acts as a cough suppressant, chlorpheniramine provides antihistamine activity, and phenylephrine acts as a nasal decongestant. An official DailyMed label for this exact-strength combination lists temporary relief of cough, runny nose, sneezing, itching and nasal congestion.
Key Benefits of MEXACOF-DX
- Combines Dextromethorphan Hydrobromide 10 mg + Chlorpheniramine Maleate 2 mg + Phenylephrine HCl 5 mg
- Helps temporarily suppress cough
- Supports relief from runny nose and sneezing
- Helps relieve nasal congestion
- Provides antihistamine support for allergy-related symptoms
- Combines three complementary actions in one oral formulation
- Convenient liquid dosage form
- Supplied in a 60 ML pack with carton
How MEXACOF-DX Works
MEXACOF-DX contains three active ingredients with different functions.
Dextromethorphan Hydrobromide acts as an antitussive and helps reduce the urge to cough.
Chlorpheniramine Maleate is an antihistamine that reduces the effects of histamine involved in allergic symptoms such as sneezing, itching and runny nose.
Phenylephrine HCl is a nasal decongestant that helps reduce swelling of the nasal passages, making nasal breathing easier.
Therefore, the combination can provide broader symptomatic relief when cough occurs together with cold or allergy-related nasal symptoms.
Common Side Effects of MEXACOF-DX
Possible side effects can vary depending on the individual. They may include:
- Drowsiness
- Dizziness
- Dry mouth
- Nausea
- Stomach discomfort
- Headache
- Difficulty sleeping or nervousness
Chlorpheniramine can cause drowsiness, while phenylephrine may cause effects such as nervousness or increased blood pressure in susceptible individuals.
Important Safety Information
- Use MEXACOF-DX according to the product label or as directed by a healthcare professional.
- Do not use this combination to sedate or make a child sleepy.
- Combination cough-and-cold products containing antihistamines or decongestants require particular caution in young children. FDA advises against giving these products to children under 2 years of age, and many OTC products carry labelling stating not to use under 4 years of age. Follow the applicable approved Indian product label and medical advice for paediatric use.
- Do not exceed the recommended dose.
- Avoid taking another cough, cold or allergy medicine containing dextromethorphan, chlorpheniramine or phenylephrine at the same time unless advised by a healthcare professional.
- Do not use with an MAOI or within 14 days of stopping an MAOI unless specifically advised by a healthcare professional.
- Chlorpheniramine may cause drowsiness. Avoid activities requiring alertness if affected.
- Use caution in people with high blood pressure, heart disease, thyroid disease, glaucoma or urinary-retention problems.
- Tell your healthcare professional about all medicines and supplements being taken.
- Seek medical attention if cough persists, becomes severe, produces blood, or occurs with breathing difficulty, chest pain or other concerning symptoms.
- Keep out of reach of children.
Dosage & Administration
Use MEXACOF-DX only according to the dosage instructions provided on the product label or as directed by a healthcare professional.
The appropriate dose depends on factors such as age, clinical condition and the exact concentration of the formulation. Therefore, the 60 ML bottle size should not be used to calculate the dose.
Shake the bottle well before administration and measure each dose using the supplied measuring device.
Do not exceed the recommended quantity or frequency.
Storage
Store MEXACOF-DX according to the manufacturer’s labelled storage conditions.
- Keep the bottle tightly closed.
- Protect from excessive heat, moisture and direct sunlight.
- Store in the original carton where appropriate.
- Do not freeze unless specifically permitted by the manufacturer.
- Keep out of reach of children.
- Check the product label for the exact storage temperature and expiry information.




