Description
MEXACOF-DMR contains Dextromethorphan Hydrobromide 10 mg, Phenylephrine Hydrochloride 5 mg and Chlorpheniramine Maleate 2 mg. This combination brings together a cough suppressant, nasal decongestant and antihistamine to provide temporary relief from cough and common cold or allergy-related symptoms such as nasal congestion, runny nose and sneezing.
For related formulations and therapeutic segments, explore the Medhexa Pharma Tablet Range for additional product information.
Therapeutic Segment
Cough & Cold Care | Antitussives | Antihistamines | Nasal Decongestants
Uses of MEXACOF-DMR
MEXACOF-DMR may be used for temporary relief of symptoms associated with the common cold and certain upper respiratory allergies, when appropriate for the patient. These symptoms may include:
- Cough caused by minor throat or bronchial irritation
- Nasal congestion or a blocked nose
- Runny nose
- Sneezing
- Itching of the nose or throat
- Allergy-related nasal symptoms
The combination addresses different symptoms through its three active ingredients. Dextromethorphan acts as a cough suppressant, Chlorpheniramine provides antihistamine activity, and Phenylephrine acts as a nasal decongestant.
Key Benefits of MEXACOF-DMR
- Contains Dextromethorphan Hydrobromide 10 mg
- Contains Phenylephrine Hydrochloride 5 mg
- Contains Chlorpheniramine Maleate 2 mg
- Combines cough-suppressant, antihistamine and decongestant actions
- Helps provide temporary relief from cough and selected cold-related symptoms
- May help relieve nasal congestion, runny nose and sneezing
- Available as an oral tablet
- Supplied in 10 × 10 BLISTER packaging
How MEXACOF-DMR Works
Each ingredient in MEXACOF-DMR contributes a different action.
Dextromethorphan Hydrobromide acts as an antitussive and helps suppress the cough reflex, making it useful for cough associated with minor throat and bronchial irritation.
Phenylephrine Hydrochloride is a nasal decongestant. It acts on blood vessels in the nasal passages to reduce swelling and help improve nasal airflow.
Chlorpheniramine Maleate is an antihistamine that helps reduce histamine-related symptoms such as sneezing, runny nose and itching.
Common Side Effects of MEXACOF-DMR
Some people may experience side effects related to one or more ingredients, such as:
- Drowsiness or sleepiness
- Dizziness
- Dry mouth, nose or throat
- Nausea or stomach discomfort
- Headache
- Nervousness or restlessness
- Difficulty sleeping
- Increased blood pressure or palpitations in susceptible individuals
Chlorpheniramine can cause drowsiness, so caution is advised when driving or operating machinery. The response can vary between individuals.
Important Safety Information
Use MEXACOF-DMR according to the directions provided by a healthcare professional or the product label.
- Do not exceed the recommended dose.
- Chlorpheniramine may cause drowsiness. Avoid driving or operating machinery if you feel sleepy or less alert.
- Avoid alcohol or other medicines that can increase drowsiness unless your healthcare professional advises otherwise.
- Tell your doctor if you have high blood pressure, heart disease, thyroid disease, glaucoma, breathing problems or difficulty passing urine.
- Phenylephrine may require particular caution in people with cardiovascular conditions or high blood pressure.
- Tell your healthcare professional about all medicines you take.
- Do not use with monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping an MAOI, unless specifically advised by a healthcare professional.
- Do not use this combination simply to make a child sleepy.
- Seek medical advice if cough persists, becomes severe, or is accompanied by concerning symptoms such as difficulty breathing, chest pain or high fever.
For additional reference, see the DailyMed drug-label information for a comparable dextromethorphan, chlorpheniramine and phenylephrine combination.
Dosage & Administration
The appropriate dose of MEXACOF-DMR depends on the patient’s age, symptoms, medical history and the specific product directions.
Take the tablets exactly as directed by your healthcare professional or according to the approved product label. Swallow the tablet with water and do not exceed the recommended daily dose.
Because combination cough-and-cold products can contain multiple active ingredients, do not combine MEXACOF-DMR with another cough, cold, antihistamine or decongestant product without checking the ingredients first.
If symptoms do not improve or become worse, consult a healthcare professional.
Storage
- Store MEXACOF-DMR in a cool and dry place.
- Protect from excessive heat, moisture and direct sunlight.
- Keep the tablets in their original blister packaging until use.
- Keep out of reach of children.
- Follow the storage conditions printed on the product packaging.




