Description
ITRAZEX-200 contains Itraconazole 200 mg, an oral triazole antifungal medicine used to treat selected fungal infections. Itraconazole works by interfering with the production of ergosterol, an essential component of fungal cell membranes. As a result, it helps inhibit the growth of susceptible fungi. Healthcare professionals may prescribe Itraconazole for specific fungal infections based on the site of infection, causative organism and clinical condition.
For related antifungal formulations and other pharmaceutical products, explore the Medhexa Pharma product range.
Therapeutic Segment
Antifungal Therapy | Dermatology | Systemic Fungal Infections | Azole Antifungals | Anti-Infective Care
Uses of ITRAZEX-200
ITRAZEX-200 may be prescribed for selected fungal infections caused by susceptible organisms. Itraconazole capsules have approved uses that include certain systemic fungal infections and fungal nail infections. The exact treatment depends on the type, location and severity of the infection.
Potential clinical uses include:
- Selected dermatophyte fungal infections
- Certain fungal nail infections
- Blastomycosis
- Histoplasmosis
- Selected aspergillosis infections
- Other susceptible fungal infections when a healthcare professional considers Itraconazole appropriate
Itraconazole does not treat bacterial or viral infections. Therefore, healthcare professionals should confirm the suspected or identified fungal infection before selecting antifungal therapy.
Key Benefits of ITRAZEX-200
ITRAZEX-200 provides antifungal activity through its active ingredient, Itraconazole.
- Contains Itraconazole 200 mg
- Belongs to the triazole class of antifungal medicines
- Interferes with fungal ergosterol production
- Helps inhibit the growth of susceptible fungi
- Supports treatment of selected superficial and systemic fungal infections
- Available as an oral capsule dosage form
- Supplied in convenient 10 × 10 blister packaging
Moreover, Itraconazole has activity against several medically important fungi, although susceptibility can vary between organisms and individual infections.
How ITRAZEX-200 Works
Itraconazole blocks an important fungal enzyme involved in ergosterol synthesis. Ergosterol plays an essential role in maintaining the structure and function of fungal cell membranes.
By reducing ergosterol production, Itraconazole disrupts fungal cell membrane formation and function. Consequently, the medicine can inhibit the growth of susceptible fungi.
Because different fungal infections require different treatment approaches, the healthcare professional should select the appropriate dose and treatment duration according to the infection.
Common Side Effects of ITRAZEX-200
Some patients may experience side effects while taking Itraconazole. Common or reported effects can include:
- Nausea
- Abdominal pain
- Diarrhea
- Headache
- Indigestion
- Constipation
- Dizziness
- Vomiting
- Increased or decreased appetite
However, side effects can vary depending on the patient, treatment duration and underlying condition.
Seek medical attention promptly if you experience symptoms such as shortness of breath, swelling of the legs or ankles, sudden weight gain, unusual tiredness, yellowing of the skin or eyes, dark urine or persistent nausea and vomiting. These symptoms can indicate serious cardiac or liver problems and require medical evaluation.
Important Safety Information
Use ITRAZEX-200 only under the guidance of a qualified healthcare professional.
Itraconazole carries important cardiac safety warnings. The medicine can cause or worsen congestive heart failure in susceptible patients. Patients with a history of heart failure or ventricular dysfunction require careful medical assessment before treatment.
In addition, Itraconazole can cause serious liver problems, although these reactions occur rarely. Contact a healthcare professional promptly if you develop unusual fatigue, loss of appetite, persistent nausea or vomiting, jaundice, dark urine or pale stools.
Itraconazole also interacts with many medicines because it can strongly affect CYP3A4-mediated drug metabolism. Therefore, tell your healthcare professional about all prescription medicines, over-the-counter medicines, vitamins and supplements you take before starting treatment. Some drug combinations can cause serious or potentially life-threatening reactions.
Furthermore, Itraconazole absorption from capsules can decrease when stomach acidity falls. Antacids and medicines that reduce gastric acid can therefore affect absorption. Itraconazole capsules should generally be taken after a full meal and swallowed whole.
Patients with liver disease, kidney problems, heart disease or a history of drug allergies should inform their healthcare professional before treatment.
Pregnant patients and those planning pregnancy should also discuss Itraconazole treatment with their healthcare professional, particularly when treatment involves fungal nail infections.
Dosage & Administration
Take ITRAZEX-200 exactly as prescribed by your healthcare professional. The appropriate dose and treatment duration depend on the type of fungal infection, its severity, the patient’s medical condition and the response to therapy.
Itraconazole capsule absorption generally improves when patients take the capsules after a full meal. Swallow the capsule whole with water rather than crushing or chewing it.
Do not change the dose or stop treatment early unless your healthcare professional advises you to do so. Fungal infections often require a specific treatment duration, so completing the prescribed course helps support appropriate treatment.
Also, do not take antacids or acid-reducing medicines around the same time without discussing their use with your healthcare professional, as reduced stomach acidity can affect Itraconazole capsule absorption.
Storage
Store ITRAZEX-200 in a cool, dry place away from excessive heat, moisture and direct sunlight.
Keep the capsules in their original blister packaging until use. In addition, keep the medicine out of reach of children.
Follow the specific storage instructions printed on the product packaging.
