FEXOEX-M

Description

FEXOEX-M is a combination oral syrup containing Fexofenadine 30 mg and Montelukast 4 mg. This formulation combines an antihistamine with a leukotriene receptor antagonist to support the management of allergic symptoms and selected respiratory conditions when prescribed by a healthcare professional.

For related allergy, respiratory and pharmaceutical formulations, explore the Medhexa Pharma product range for additional products and therapeutic segments.

Therapeutic Segment

Anti-Allergic | Allergic Rhinitis | Respiratory Allergy | Antihistamine | Leukotriene Receptor Antagonist | Oral Syrup

Uses of FEXOEX-M

FEXOEX-M may be prescribed for the management of allergic symptoms where treatment with both an antihistamine and montelukast is considered appropriate.

It may help manage:

• Sneezing associated with allergic rhinitis.
• Runny or itchy nose.
• Nasal allergy symptoms and congestion.
• Itching associated with allergic conditions.
• Allergic skin symptoms such as urticaria and itching, where fexofenadine is clinically appropriate.
• Respiratory allergy symptoms associated with allergic rhinitis.
• Selected asthma-related symptoms when montelukast is specifically prescribed as part of an appropriate asthma treatment plan.

Fexofenadine is an antihistamine used to relieve symptoms such as runny nose, sneezing, itchy nose or throat, and itchy or watery eyes associated with upper respiratory allergies.

Montelukast is approved for allergic rhinitis and for prevention and long-term treatment of asthma in appropriate patients. However, it is not a rescue medicine for an acute asthma attack.

Key Benefits of FEXOEX-M

• Combines Fexofenadine 30 mg and Montelukast 4 mg in one oral syrup formulation.
• Fexofenadine helps reduce histamine-related allergic symptoms.
• Helps relieve sneezing, runny nose and nasal itching associated with allergies.
• Fexofenadine can also help manage itching associated with urticaria.
• Montelukast blocks leukotriene receptors involved in allergic and airway inflammatory responses.
• May provide supportive control of respiratory allergy symptoms.
• Convenient liquid dosage form.
• Supplied in a 60 ML syrup pack.

How FEXOEX-M Works

FEXOEX-M combines two medicines with different mechanisms.

Fexofenadine is a selective H1-antihistamine. It reduces the effects of histamine, helping relieve common allergy symptoms such as sneezing, runny nose, itching and watery eyes.

Montelukast blocks leukotriene receptors. Leukotrienes are inflammatory mediators involved in allergic rhinitis and asthma. By blocking these receptors, montelukast can help control certain allergy and asthma symptoms.

Therefore, the combination provides complementary antihistamine and leukotriene-targeting activity for selected allergic and respiratory conditions.

Common Side Effects of FEXOEX-M

Possible side effects can vary between patients. They may include:

• Headache
• Nausea
• Stomach discomfort
• Diarrhoea
• Dizziness
• Fatigue
• Upper respiratory symptoms
• Dry mouth

Fexofenadine is generally considered less sedating than older antihistamines, although some patients may still experience dizziness or drowsiness.

Montelukast can cause headache and other adverse effects. More importantly, it carries a boxed warning concerning serious neuropsychiatric events, including changes in behavior or mood and suicidal thoughts or actions.

Contact a healthcare professional promptly if unusual mood, behavior or sleep changes develop.

Important Safety Information

FEXOEX-M should be used according to the product label and healthcare professional’s advice.

• Do not exceed the recommended dose.
• Do not use FEXOEX-M as a rescue medicine for sudden asthma attacks.
• Patients with acute breathing difficulty or a severe asthma attack require appropriate emergency or rescue treatment.
• Montelukast has an FDA Boxed Warning for serious neuropsychiatric events. Patients and caregivers should watch for changes in mood, behavior, sleep or thinking.
• For allergic rhinitis, FDA recommends reserving montelukast for patients who do not respond adequately to or cannot tolerate alternative allergy medicines.
• Contact a healthcare professional immediately if suicidal thoughts, unusual behavior, severe mood changes or other significant mental health symptoms occur.
• Inform your doctor about kidney disease or other significant medical conditions.
• Fexofenadine dosage may require consideration in patients with kidney impairment.
• Avoid taking medicines that contain the same active ingredients unless specifically advised.
• Inform your healthcare professional about all prescription medicines, over-the-counter products and supplements you use.
• Keep the product out of reach of children.
• Do not use after the expiry date.

For detailed information regarding montelukast’s safety warning, refer to the FDA Drug Safety Communication.

Dosage & Administration

The dosage of FEXOEX-M should be determined according to the approved product label, patient’s age and clinical condition, and the healthcare professional’s recommendation.

The supplied product information does not state whether the listed strengths are per 5 mL, per 10 mL or another measured volume. Therefore, the dose should not be calculated from the 60 ML bottle size.

• Use only the prescribed or labelled dose.
• Measure the syrup with a suitable measuring device.
• Do not use a household spoon for accurate dosing.
• Shake the bottle well before use if instructed on the product label.
• Do not increase the dose or frequency without medical advice.
• Pediatric use should follow the age-specific directions on the approved product label.

Storage

• Store FEXOEX-M according to the conditions stated on the product label.
• Keep the bottle tightly closed when not in use.
• Protect from excessive heat, moisture and direct sunlight.
• Keep out of reach of children.
• Do not use after the expiry date.
• Follow the manufacturer’s instructions regarding storage after opening.