Description

CEPXONE-S 1.5 GM

CEPXONE-S 1.5 GM contains Cefoperazone 1000 mg + Sulbactam 500 mg Injection, a combination antibiotic used for selected bacterial infections when prescribed by a healthcare professional. Cefoperazone provides antibacterial activity, while Sulbactam helps inhibit certain beta-lactamase enzymes that can reduce the activity of some beta-lactam antibiotics.

The combination may help manage susceptible bacterial infections involving the respiratory tract, urinary tract and abdomen. In addition, healthcare professionals may prescribe it for serious infections such as septicaemia or meningitis when clinically appropriate. Therefore, a qualified healthcare professional should administer CEPXONE-S 1.5 GM.

For other injectable formulations, you can also explore the MedHexa Injectable Range.

Therapeutic Segment

Antibiotic | Anti-Infective | Cephalosporin Antibiotic | Injectable

Uses of CEPXONE-S 1.5 GM

CEPXONE-S 1.5 GM may help manage certain bacterial infections caused by susceptible microorganisms.

Healthcare professionals may prescribe it for selected infections involving:

• Respiratory tract infections
• Urinary tract infections
• Intra-abdominal infections
• Septicaemia
• Meningitis
• Other susceptible bacterial infections

However, the appropriate use depends on the type and severity of the infection, the causative organism and the patient’s clinical condition. Therefore, use this antibiotic only under the guidance of a qualified healthcare professional.

Key Benefits of CEPXONE-S 1.5 GM

CEPXONE-S 1.5 GM combines Cefoperazone with Sulbactam to provide antibacterial activity against susceptible bacteria.

• Contains Cefoperazone 1000 mg
• Contains Sulbactam 500 mg
• Provides antibacterial activity against susceptible bacteria
• Sulbactam helps inhibit certain beta-lactamase enzymes
• May help manage selected respiratory tract infections
• May help manage certain urinary tract infections
• May help manage selected intra-abdominal infections
• May be used for serious bacterial infections such as septicaemia and meningitis
• Provides a convenient injectable formulation

Furthermore, Sulbactam can inhibit certain beta-lactamase enzymes produced by bacteria. As a result, it can help protect Cefoperazone from enzymatic breakdown and support its antibacterial activity against susceptible organisms.

How Cefoperazone & Sulbactam Works

Cefoperazone belongs to the cephalosporin group of antibiotics. It interferes with bacterial cell-wall formation. Consequently, susceptible bacteria cannot maintain their cell walls, which can lead to bacterial death.

Sulbactam works as a beta-lactamase inhibitor. Certain bacteria produce beta-lactamase enzymes that can break down some beta-lactam antibiotics. Sulbactam inhibits several of these enzymes and, therefore, can help protect Cefoperazone from enzymatic breakdown.

Together, these actions help the combination manage selected bacterial infections when the causative organisms respond to the treatment.

Side Effects of CEPXONE-S 1.5 GM

Some patients may experience side effects during treatment with Cefoperazone and Sulbactam.

Possible effects include:

• Diarrhea
• Nausea
• Vomiting
• Abdominal discomfort
• Injection-site pain or irritation
• Skin rash
• Headache
• Changes in liver function tests

These effects may not affect everyone. However, inform your healthcare professional if any symptom becomes severe, persistent or unusual.

In addition, seek immediate medical attention if you develop difficulty breathing, facial swelling, severe skin reactions or other signs of a serious allergic reaction.

Safety Information

CEPXONE-S 1.5 GM requires administration by a qualified healthcare professional.

Before treatment, inform your doctor if you:

• Have an allergy to Cefoperazone, Sulbactam, cephalosporins or penicillin antibiotics
• Have liver disease
• Have kidney problems
• Have a history of gastrointestinal disease or colitis
• Have problems with blood clotting or vitamin K deficiency
• Are pregnant or breastfeeding
• Take anticoagulants or other prescription medicines

Also, tell your healthcare professional about any previous serious reaction to antibiotics.

Cefoperazone can affect vitamin K-dependent clotting in some patients. Therefore, patients with risk factors for bleeding may need appropriate monitoring.

Furthermore, antibiotic treatment can sometimes cause antibiotic-associated diarrhea, including Clostridioides difficile-associated diarrhea. Seek medical advice if severe or persistent diarrhea develops during or after treatment.

For additional professional information, refer to the DailyMed Cefoperazone and Sulbactam Information.

Dosage & Administration

A qualified healthcare professional should determine and administer the appropriate dose of CEPXONE-S 1.5 GM.

• The healthcare professional should prepare the injection using the appropriate diluent and technique.
• The healthcare professional should select the appropriate route according to the prescribing information.
• The required dose depends on the type and severity of infection.
• Treatment duration depends on the infection and the patient’s clinical response.
• Do not self-administer the injection.
• Do not change the prescribed dose without medical advice.

The pack includes Vial + Water. Therefore, the healthcare professional should use the supplied water according to the product instructions and appropriate preparation requirements.

Cefoperazone 1000 mg & Sulbactam 500 mg Information

CEPXONE-S 1.5 GM contains Cefoperazone 1000 mg + Sulbactam 500 mg in injectable form.

Cefoperazone interferes with bacterial cell-wall synthesis and, therefore, helps control susceptible bacteria. Meanwhile, Sulbactam inhibits certain beta-lactamase enzymes and can help protect Cefoperazone from enzymatic breakdown.

As a result, the combination may help manage selected bacterial infections when the causative organisms are susceptible.

Storage

• Store CEPXONE-S 1.5 GM according to the conditions stated on the product label.
• Keep the vial in its original packaging.
• Protect the product from excessive heat and direct sunlight.
• Store the supplied water according to the product instructions.
• Keep the medicine out of reach of children.
• Do not use the product after the expiry date.
• Finally, always follow the storage conditions printed on the product packaging.