TELMIZN-H

Description

TELMIZN-H contains Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg in tablet form. This combination brings together an angiotensin II receptor blocker (ARB) and a thiazide diuretic to help lower blood pressure in appropriate patients. Telmisartan helps relax blood vessels by blocking the action of angiotensin II, while Hydrochlorothiazide promotes the removal of excess sodium and water through the urine.

For related cardiovascular and hypertension formulations, explore the Medhexa Pharma product range for pharmaceutical products and business enquiries.

Therapeutic Segment

Cardiovascular Care | Antihypertensive Therapy | Blood Pressure Management | ARBs | Diuretics

Uses of TELMIZN-H

TELMIZN-H may be prescribed as part of a treatment plan for:

• High blood pressure (hypertension)
• Patients requiring combination antihypertensive therapy
• Blood pressure that remains inadequately controlled with an appropriate single-agent treatment
• Long-term blood pressure management when the combination is considered clinically appropriate

Lowering blood pressure can help reduce the risk of cardiovascular events such as stroke and myocardial infarction. The exact treatment approach depends on the patient’s blood pressure, medical history, response to therapy and other risk factors.

Key Benefits of TELMIZN-H

• Dual-action blood pressure management: Combines an ARB with a thiazide diuretic.
• Telmisartan 40 mg: Helps block angiotensin II-mediated blood-vessel constriction.
• Hydrochlorothiazide 12.5 mg: Helps remove excess sodium and water, contributing to blood-pressure reduction.
• Combination therapy: Provides two complementary antihypertensive mechanisms in one tablet.
• Supports long-term hypertension management: May be used when combination treatment is appropriate.
• Convenient oral formulation: Supplied as an easy-to-administer tablet.

How TELMIZN-H Works

Telmisartan is an angiotensin II receptor blocker (ARB). It blocks the binding of angiotensin II to AT1 receptors. As a result, blood vessels can relax and the effects of angiotensin II that promote vasoconstriction and aldosterone activity are reduced. This helps lower blood pressure.

Hydrochlorothiazide is a thiazide diuretic. It increases the excretion of sodium and water by the kidneys. This reduces fluid volume and contributes to lower blood pressure.

Together, the two ingredients provide complementary mechanisms for blood-pressure control.

Common Side Effects of TELMIZN-H

Some people may experience side effects during treatment. Possible effects include:

• Dizziness
• Headache
• Fatigue
• Nausea
• Stomach discomfort
• Diarrhoea
• Increased urination
• Changes in blood electrolyte levels
• Low blood pressure, particularly in susceptible patients

Hydrochlorothiazide may affect sodium, potassium and other electrolyte levels, while telmisartan can also alter potassium levels and kidney function. Healthcare professionals may monitor blood pressure, kidney function and electrolytes when appropriate.

Important Safety Information

Use TELMIZN-H only according to the advice of a qualified healthcare professional.

Blood Pressure and Dehydration

TELMIZN-H can lower blood pressure and may cause dizziness, particularly when treatment begins or when fluid levels are low.

Tell your doctor if you have vomiting, diarrhoea, excessive sweating or another condition that may cause dehydration.

Kidney Function and Electrolytes

Telmisartan and hydrochlorothiazide can affect kidney function and electrolyte levels. Your healthcare professional may monitor kidney function, potassium, sodium and other laboratory values when clinically appropriate.

Tell your doctor if you have kidney disease or a history of electrolyte abnormalities.

Potassium Precautions

Telmisartan can increase blood potassium levels, while hydrochlorothiazide can lower potassium levels. The overall effect can vary between patients.

Do not use potassium supplements or potassium-containing salt substitutes unless your healthcare professional recommends them.

Liver-Related Precautions

Tell your doctor if you have liver disease or biliary obstruction. Current prescribing information recommends close medical supervision when initiating the 40 mg/12.5 mg combination in patients with biliary obstructive disorders or hepatic insufficiency, and the combination is not recommended in severe hepatic impairment.

Important Medicine Interactions

Tell your healthcare professional about all medicines, vitamins and supplements you use.

Important interactions can occur with medicines such as:

• Other blood-pressure medicines
• Potassium supplements or potassium-containing salt substitutes
• Potassium-sparing diuretics
• Lithium
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Medicines that affect kidney function or electrolyte balance

Your healthcare professional can determine whether dose adjustments or additional monitoring are required.

Pregnancy

Telmisartan should not be used during pregnancy, particularly after pregnancy is detected, because medicines that act directly on the renin-angiotensin system can cause fetal harm. Tell your healthcare professional if you are pregnant, planning pregnancy or become pregnant during treatment.

For detailed prescribing and safety information, refer to the DailyMed Telmisartan and Hydrochlorothiazide prescribing information.

Dosage & Administration

Take TELMIZN-H exactly as prescribed by your healthcare professional.

The appropriate dose depends on the patient’s blood pressure, previous antihypertensive treatment, kidney and liver function, response to therapy and other medicines.

The 40 mg/12.5 mg strength is an established telmisartan/hydrochlorothiazide combination. Current prescribing information describes once-daily administration for the combination, although the appropriate regimen for an individual patient must follow the prescription and approved product information.

Take the tablet with water and follow the dosing schedule provided by your healthcare professional.

Do not change the dose or stop treatment without medical advice. If you miss a dose, follow the instructions provided by your healthcare professional rather than taking an extra tablet.

Storage

• Store TELMIZN-H in a cool, dry place.
• Protect the tablets from excessive heat and moisture.
• Keep the tablets in their original ALU-ALU packaging until use.
• Protect from direct sunlight.
• Keep the tablets in the blister until immediately before administration because telmisartan/hydrochlorothiazide tablets can be moisture-sensitive.
• Keep out of the sight and reach of children.
• Do not use the product after the expiry date printed on the pack.