Description
CILPEX-T 40 contains Telmisartan I.P. 40 mg and Cilnidipine I.P. 10 mg in tablet form. Telmisartan is an angiotensin II receptor blocker (ARB) that lowers blood pressure by blocking the action of angiotensin II, while Cilnidipine is a calcium channel blocker that helps relax blood vessels. Together, this combination provides two complementary mechanisms for blood pressure control in patients for whom combination antihypertensive therapy is prescribed.
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Therapeutic Segment
Cardiovascular Care | Antihypertensives | ARBs | Calcium Channel Blockers
Uses of CILPEX-T 40
CILPEX-T 40 may be prescribed for the management of hypertension (high blood pressure) when treatment with more than one antihypertensive mechanism is considered appropriate.
It may help:
- Lower elevated blood pressure
- Support ongoing blood pressure control
- Reduce vascular resistance through complementary mechanisms
- Provide combination antihypertensive therapy when a single medicine does not provide adequate control
Telmisartan is indicated for the treatment of hypertension, while Cilnidipine is an L/N-type calcium channel blocker used in hypertension management. The exact use of CILPEX-T 40 should follow the prescribing decision of a qualified healthcare professional.
Key Benefits of CILPEX-T 40
- Dual antihypertensive action: Combines an ARB with a calcium channel blocker.
- Supports blood pressure control: Both ingredients act through different pathways to lower blood pressure.
- Telmisartan 40 mg: Blocks angiotensin II receptors, helping reduce vasoconstriction and blood-pressure-raising effects.
- Cilnidipine 10 mg: Blocks L-type and N-type calcium channels and promotes vascular relaxation.
- Convenient tablet formulation: Provides two antihypertensive ingredients in one oral dosage form.
- Suitable for long-term therapy when prescribed: Treatment duration should always follow individual medical advice.
How CILPEX-T 40 Works
Telmisartan blocks the angiotensin II type 1 (AT1) receptor. Angiotensin II normally causes blood vessels to constrict and contributes to sodium and fluid retention. By blocking its action, telmisartan helps reduce vascular resistance and blood pressure.
Cilnidipine is a dihydropyridine calcium channel blocker with activity at both L-type and N-type calcium channels. L-type channel blockade promotes relaxation of vascular smooth muscle, while N-type channel blockade can reduce sympathetic nerve activity. These actions contribute to its antihypertensive effect.
Therefore, CILPEX-T 40 combines two complementary approaches to blood pressure management.
Common Side Effects of CILPEX-T 40
Some people may experience:
- Dizziness or light-headedness
- Headache
- Weakness or fatigue
- Low blood pressure
- Swelling of the ankles or feet
- Palpitations
- Nausea or stomach discomfort
Because both medicines can lower blood pressure, dizziness or light-headedness may occur, particularly when treatment starts or the dose changes.
Important Safety Information
Use CILPEX-T 40 only according to the prescription of a healthcare professional.
- Do not stop the medicine suddenly without medical advice, even if you feel well. High blood pressure may not produce noticeable symptoms.
- Monitor blood pressure regularly as recommended.
- Tell your doctor if you have kidney or liver problems, heart conditions, low blood pressure or problems with fluid or salt balance.
- Telmisartan can affect kidney function and potassium levels, so monitoring may be required in some patients.
- Avoid potassium supplements or potassium-containing salt substitutes unless your healthcare professional recommends them.
- Tell your doctor about all medicines you take, particularly other blood-pressure medicines, ACE inhibitors, potassium-sparing medicines, potassium supplements or medicines that can affect kidney function.
- Telmisartan should not be used during pregnancy. Medicines that act directly on the renin-angiotensin system can cause serious fetal harm. If pregnancy occurs, contact your healthcare professional promptly.
- Cilnidipine may cause dizziness or low blood pressure. Take care when standing up quickly, especially when beginning treatment.
- Seek medical attention for severe dizziness, fainting, facial or throat swelling, difficulty breathing, or other signs of a serious reaction.
For additional information about telmisartan’s prescribing precautions, refer to the DailyMed Telmisartan prescribing information.
Dosage & Administration
Take CILPEX-T 40 exactly as prescribed by your doctor.
The appropriate dose depends on blood pressure levels, response to treatment, other medicines and individual health conditions. Telmisartan itself is commonly administered once daily, with or without food, but the dosing schedule for this fixed-dose combination should follow the product prescription rather than being adjusted independently.
Do not change the dose or stop treatment without consulting your healthcare professional.
Storage
- Store at room temperature in a dry place.
- Keep the tablets protected from excessive heat and moisture.
- Keep them in the original packaging until use.
- Keep out of the sight and reach of children.
- Do not use after the expiry date printed on the pack.
