Description
MEXACLAV-CV contains Amoxycillin Trihydrate 200 mg and Potassium Clavulanate 28.5 mg per 5 mL of reconstituted suspension. It is an oral antibiotic combination containing amoxicillin, a penicillin-class antibacterial, and clavulanate, a beta-lactamase inhibitor. Together, these ingredients help treat selected bacterial infections caused by susceptible organisms.
MEXACLAV-CV is supplied as a Dry Syrup and may be prescribed for bacterial infections involving areas such as the respiratory tract, sinuses and urinary tract when the causative bacteria are susceptible. Antibiotic treatment should always follow the healthcare professional’s diagnosis and prescription.
For related formulations and therapeutic segments, explore the Medhexa Pharma Products range.
Therapeutic Segment
Antibiotics | Penicillin Antibiotics | Dry Syrups | Pediatric & General Anti-Infective Care
Uses of MEXACLAV-CV
MEXACLAV-CV may be prescribed for selected bacterial infections, including:
- Bacterial sinusitis
- Bronchitis caused by susceptible bacteria
- Bacterial tonsillitis
- Urinary tract infections
- Other susceptible bacterial infections as determined by a healthcare professional
Amoxicillin/clavulanate oral suspension has established use for several respiratory and urinary bacterial infections. Current prescribing information also includes sinusitis and lower respiratory tract infections among clinical uses, depending on the patient’s age and clinical condition.
It should not be used for common viral infections such as uncomplicated viral cold or influenza because antibiotics do not treat viral infections.
Key Benefits of MEXACLAV-CV
- Combines Amoxycillin Trihydrate and Clavulanate in an oral dry-syrup formulation.
- Provides antibacterial activity against susceptible organisms.
- Clavulanate helps inhibit certain beta-lactamase enzymes that can otherwise reduce amoxicillin activity.
- Suitable for patients who require an oral suspension rather than tablets or capsules.
- May be prescribed for selected bacterial respiratory infections.
- May support treatment of susceptible sinus and urinary tract infections.
- The dry-syrup format allows preparation as an oral suspension according to the product instructions.
How MEXACLAV-CV Works
Amoxycillin works by interfering with bacterial cell-wall synthesis. This weakens the bacterial cell wall and can lead to bacterial death.
Some bacteria produce beta-lactamase enzymes that can break down certain penicillin antibiotics. Clavulanate inhibits several of these enzymes, helping protect amoxicillin from enzymatic breakdown and extending its antibacterial activity against susceptible beta-lactamase-producing organisms.
Therefore, MEXACLAV-CV combines two complementary antibacterial components rather than relying on amoxicillin alone.
Common Side Effects of MEXACLAV-CV
Some patients may experience side effects such as:
- Diarrhea
- Nausea
- Vomiting
- Abdominal discomfort
- Indigestion
- Skin rash
- Headache
Most gastrointestinal effects are mild, but persistent or severe diarrhea requires medical attention because antibiotic treatment can sometimes cause Clostridioides difficile-associated diarrhea.
Serious allergic reactions can also occur, particularly in people with a history of severe reactions to penicillin or other beta-lactam antibiotics.
Important Safety Information
MEXACLAV-CV should be used only when prescribed by a qualified healthcare professional.
- Do not use it if there is a history of serious allergy to amoxicillin, clavulanate, penicillins or other beta-lactam antibiotics.
- Tell the healthcare professional about any previous antibiotic allergy.
- A history of liver problems or cholestatic jaundice associated with amoxicillin/clavulanate requires particular caution.
- Stop the medicine and seek urgent medical help if signs of a serious allergic reaction develop.
- Severe or persistent diarrhea during or after treatment requires medical assessment.
- Antibiotic misuse or unnecessary use can contribute to antimicrobial resistance.
- Tell the healthcare professional about other medicines being taken, including anticoagulants and other prescription medicines.
- Complete the prescribed course unless the healthcare professional advises otherwise.
The official prescribing information lists serious hypersensitivity reactions, hepatic dysfunction and C. difficile-associated diarrhea among important warnings and precautions.
Dosage & Administration
The appropriate dose of MEXACLAV-CV depends on factors such as age, body weight, infection type, severity of infection, kidney function and clinical response. Therefore, the exact dose should be determined by the prescribing healthcare professional.
For pediatric patients, official labeling calculates dosing according to the amoxicillin component and body weight. For the 200 mg/28.5 mg per 5 mL formulation, dosing schedules can differ according to infection severity and the patient’s clinical condition.
Do not calculate or administer a pediatric dose based only on the 30 mL bottle size.
Directions for Reconstitution
Prepare MEXACLAV-CV according to the instructions printed on the product label or package insert.
In general, dry amoxicillin/clavulanate suspension is prepared by adding the specified quantity of water to the powder and shaking thoroughly. The exact amount of water can vary with the manufacturer’s bottle size and formulation, so the manufacturer’s stated reconstitution volume must be followed.
After reconstitution:
- Shake the suspension well before each dose.
- Use an appropriate calibrated measuring device for accurate dosing.
- Store the reconstituted suspension under refrigeration according to the product instructions.
- Do not freeze the suspension.
- Discard unused reconstituted suspension after the period specified by the manufacturer. Official labeling for this formulation commonly specifies 10 days under refrigeration.
Storage
Before reconstitution: Store the dry powder according to the manufacturer’s labelled storage conditions and protect the container from moisture.
After reconstitution: Keep the suspension refrigerated and shake well before use. Official prescribing information for the 200 mg/28.5 mg per 5 mL formulation specifies refrigeration and disposal of unused suspension after 10 days.
Keep MEXACLAV-CV out of reach of children.
